Zanaflex 2mg Tizanidine INDIA


Zanaflex 2mg Tizanidine

Seeking relief from muscle spasticity? Discover Zanaflex, the centrally acting muscle relaxant that eases muscle tightness and pain. Perfect for those with conditions like multiple sclerosis or spinal cord injuries.

Dosage: Start with 2mg and adjust according to your needs. Remember, consistency is key; take it with or without food, but stay consistent. Max daily dose: 36mg.

Note: Side effects may include drowsiness or dizziness. Always consult your doctor before starting a new medication.

All INDIA MEDS are shipped by courier and tracking number in 48h after the payment.
Average shipping time: 2-3 weeks.

Zanaflex (Tizanidine) is a centrally acting α2-adrenergic agonist which is used as a muscle relaxant. Its main active ingredient, Tizanidine, functions primarily in the central nervous system to produce its muscle relaxant effects. The chemical name for Tizanidine is 5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole.


Tizanidine exerts its therapeutic effect by inhibiting presynaptic motor neurons, which results in a reduction of spasticity. By increasing the presynaptic inhibition of motor neurons, Tizanidine reduces the release of excitatory amino acids and decreases the firing rate of motor neurons, thus suppressing the reflex hyperactivity.


Zanaflex 2mg is indicated for the management of spasticity, which can arise from a variety of conditions including multiple sclerosis, spinal cord injury, or other neurological disorders. Spasticity is a condition where muscles become continuously contracted, causing stiffness or tightness of the muscles, and can interfere with movement, speech, and gait.

By reducing spasticity, Zanaflex helps improve muscle tone, provides relief from pain and muscle tightness, and aids in restoring normal movements.


The recommended starting dose of Zanaflex is 2mg. Depending on the individual patient’s needs and response, the dosage can be titrated at 24-hour intervals. The dose can be increased by 2-4mg until an optimal response is achieved. However, the total daily dose should not exceed 36mg. It’s important to note that treatment should be individualized according to the needs and response of the patient.

Dosing considerations:

  1. Timing with Food: Zanaflex is known to increase in its bioavailability when taken with food. Patients need to be consistent in taking Zanaflex either always with or always without food.
  2. Dosage Titration: To minimize the risk of side effects, it is advisable to titrate the dose slowly when initiating therapy.
  3. Withdrawal: Abrupt discontinuation can lead to rebound hypertension and tachycardia; it’s recommended to reduce the dose gradually.
  4. Renal Impairment: Patients with renal insufficiency may require reduced doses. It’s essential to monitor these patients closely.
  5. Elderly Patients: The elderly population might have reduced renal function; hence they may require reduced dosages.

Side Effects:

Common side effects include drowsiness, dry mouth, asthenia, dizziness, urinary tract infections, and gastrointestinal problems. It’s essential to monitor for hypotension, liver function abnormalities, and signs of central nervous system depression.

Contraindications and Warnings:

  1. Zanaflex should not be used concomitantly with CYP1A2 inhibitors like fluvoxamine or ciprofloxacin.
  2. Concomitant use of Zanaflex with other CNS depressants can potentiate the CNS effects.


Store at a temperature between 15°C to 30°C. Keep out of the reach of children.

Product Name: Zanaflex 2mg (Tizanidine)


Zanaflex 2mg is a centrally acting alpha-2 adrenergic agonist, with its primary ingredient being Tizanidine. This medication is used predominantly as an antispasmodic to provide relief from spasms, cramping, tightness of muscles, and other related conditions.

Chemical Structure:

Tizanidine hydrochloride (HCl) is a white to off-white, fine crystalline powder, odorless or with a faint characteristic odor. It’s slightly soluble in water and methanol and soluble in ethanol.


  1. Muscle Spasticity: Zanaflex is primarily indicated for the treatment of muscle spasticity. Muscle spasticity might be due to multiple sclerosis, spinal cord injuries, or other neurological disorders.
  2. Off-label uses: There have been instances where Tizanidine is used for migraines, headache disorders, and as a sleep aid. Always consult a medical professional before taking this medication for off-label purposes.

Dosage and Administration:

  1. Starting Dose: For most patients, the recommended starting dose is 2mg. Depending on the patient’s response, the dose may be increased by 2mg to 4mg increments until an optimal response is achieved.
  2. Maintenance Dose: Dosage can be gradually increased by 2mg to 4mg at each dose, with 1 to 4 days in between the increases until satisfactory reduction of muscle tone is achieved. The total daily dose should not exceed 36 mg.
  3. Dosing in Specific Populations: For elderly patients or those with renal insufficiency, dosage should be adjusted accordingly, taking into consideration the individual’s creatinine clearance.
  4. Administration: Zanaflex 2mg should be taken orally with a full glass of water. It can be taken with or without food but taking it consistently, either with food or without, will ensure more uniform absorption.


Zanaflex 2mg should not be used:

  1. By patients with hypersensitivity to Tizanidine or any other components of the tablet.
  2. Concomitantly with strong CYP1A2 inhibitors.

Side Effects:

Common side effects include dry mouth, somnolence, asthenia (weakness or fatigue), dizziness, UTI (urinary tract infection), constipation, liver function test abnormalities, vomiting, and speech disorder. This is not a complete list, and patients should consult a healthcare professional for detailed information.


Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) in a dry place and keep out of reach of children.

Note: Always consult a medical professional before starting or stopping any medication. This description does not contain all possible side effects or interactions.




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