2-Methyl-PiHP (2-Me-PiHP) is a novel synthetic compound belonging to the pyrrolidine class of stimulants. Structurally related to α-Pyrrolidinohexiophenone (α-PiHP), 2-Me-PiHP exhibits similar pharmacological effects but features a methyl substitution at the 2-position of the phenyl ring. This minor structural modification significantly impacts the compound’s receptor affinity, potency, and duration of action. 2-Me-PiHP is primarily researched for its central nervous system (CNS) stimulating properties, often compared to cathinone derivatives such as α-PVP and α-PiHP. Due to its unique chemical profile, it is widely used in pharmacological studies exploring the mechanisms of stimulant-induced dopamine release and norepinephrine uptake inhibition.
Chemical Structure and Properties
- IUPAC Name: 2-(Methylamino)-1-phenylpentan-1-one
- Molecular Formula: C13H17NO
- Molecular Weight: 203.28 g/mol
- SMILES Representation: CC(C)NC(=O)C1=CC=CC=C1
- Chemical Class: Pyrrolidine Stimulant
2-Me-PiHP is a highly lipophilic compound, enabling it to cross the blood-brain barrier efficiently. Its pharmacodynamics involve high-affinity binding to monoamine transporters, particularly the dopamine and norepinephrine transporters (DAT and NET), resulting in potent reuptake inhibition and increased synaptic neurotransmitter levels.
Effects
The effects of 2-Me-PiHP, based on anecdotal reports and laboratory studies, include:
- Stimulation: Enhanced physical and mental energy, often accompanied by heightened alertness and focus.
- Euphoria: A transient increase in mood and feelings of well-being.
- Increased Sociability: Users report heightened confidence and talkativeness.
- Cognitive Enhancement: Improved short-term memory, problem-solving abilities, and concentration.
The onset of effects is typically rapid, occurring within 15-30 minutes after administration, with peak effects observed around 1-2 hours. The total duration of action ranges from 4 to 6 hours, depending on dosage and individual metabolic factors.
Dosage Guidelines
Disclaimer: All information is provided for research purposes only. Human consumption is not advised.
- Threshold: 5-10 mg
- Light: 10-20 mg
- Common: 20-30 mg
- Strong: 30-40 mg
Due to its potency, initial doses should be conservative to mitigate adverse reactions. Laboratory protocols should emphasize precise measurement using a milligram scale.
Side Effects
Potential adverse effects include:
- Psychological: Anxiety, paranoia, agitation, and restlessness.
- Physical: Increased heart rate, hypertension, sweating, and vasoconstriction.
- Neurological: Headache, dizziness, and insomnia.
Prolonged or excessive use may exacerbate side effects, leading to tolerance, dependence, or neurotoxicity. Researchers should exercise caution during studies to limit dosage and exposure duration.
Harm Reduction
To ensure safe handling and minimize risks, the following harm reduction strategies are recommended:
Co-administration: Avoid mixing with other stimulants or depressants to reduce interaction risks.
Accurate Dosage: Utilize calibrated equipment for precise measurement.
Environment: Conduct experiments in a controlled and supervised setting.
Hydration: Maintain proper hydration levels to mitigate dehydration caused by excessive stimulation.
Breaks: Avoid repeated exposure and ensure adequate rest periods between experiments.
Why Buy 2-Me-PiHP CN from RECHEMCO?
★ We have a long trading history in the market so you benefit from our experience.
★ 2-Me-PiHP was tested and verified.
★ We accept various payment methods such as Bitcoin, Monero and bank wire.
What you will receive when you buy 2-Me-PiHP from RECHEMCO?
• One sealed aluminum foil bag containing highest grade 2-Me-PiHP
• white/yellowish crystals
• 98% Purity
benejichaser (verified owner) –
I was very much surprised by this to say the least. In a positive, I might add.
Likely is able to hold up to the high expectations, some might have, when it comes to this specific class.
Atleast, considering my expectations, that has been the case.
Rechemco –
Thank you for sharing your experience with our product. We’re pleased to hear it met your expectations for research purposes.
We want to remind all customers that our products are intended solely for laboratory research and analysis by qualified professionals. They are not for human consumption or any other unauthorized use.
Proper safety protocols should always be followed when handling any chemical substances. If you have any questions about appropriate research applications, don’t hesitate to contact us.
daggada (verified owner) –
If you Look around the net, the reviews for this substance are often reserved. After accidentially consuming some of this substance in connection with an erotic situation, the effect and the potential became obvious to us. It was pretty …. extatic.
Rechemco –
Thank you for sharing your experience and review. We’re glad to hear you had a positive encounter with the product, but we’d like to remind you that our products are strictly not intended for human consumption. Safety is our top priority, and we always recommend using the item as directed for its intended purpose.
If you have any questions about proper usage, feel free to reach out. Stay safe!