5-APB (5-(2-aminopropyl)benzofuran) is a synthetic compound from the benzofuran family, closely related to substances like MDMA in terms of its chemical structure and effects. As a research chemical, it’s gained attention for its entactogenic and psychedelic properties, offering insight into the neuropharmacology of serotonin receptor modulation and its impact on human cognition, emotion, and social behavior.

Effecten

5-APB primarily acts as a serotonin, dopamine, and norepinephrine releasing agent, with its most pronounced effects on the serotonin system, leading to feelings of empathy, warmth, and increased sociability, alongside mild to moderate psychedelic effects such as enhanced sensory perception. These effects make it of interest not only for recreational use but also for potential therapeutic applications in treating mood disorders and social anxiety.

Dosering

The effective dosage of 5-APB varies significantly among individuals, but it typically ranges from 50 to 100 mg when taken orally. Lower doses are often recommended for first-time users to minimize the risk of adverse effects. It’s crucial to start with the lowest possible dose and gradually increase to assess individual tolerance.

Bijwerkingen

Side effects can include, but are not limited to, nausea, increased heart rate, hypertension, hyperthermia, and in rare cases, serotonin syndrome, especially when combined with other serotonergic substances. Long-term effects and dependency potential remain under-researched, highlighting the importance of caution and moderation in use.

Schadebeperking

Harm reduction strategies include testing substances for purity, starting with low doses, avoiding combinations with other psychoactive substances, staying hydrated, and ensuring a safe environment when using. It’s also advisable to have a sober sitter present and to avoid driving or operating heavy machinery.

Productoverzicht:

6-APB, known as Benzofury, is a synthetic compound in the entactogen and psychedelic class, related to amphetamines and the benzofuran family. Its chemical structure is comparable to MDA and MDMA, and it acts primarily as a serotonin, dopamine, and norepinephrine releasing agent.

Effecten:

Users often report effects such as emotional enhancement, increased empathy, and euphoria, akin to those experienced with MDMA. It also induces sensory amplification, altered perception of time, and cognitive euphoria. Some may experience introspection and enhanced creativity.

Dosering:

The dosage varies based on the form (HCl or succinate) and individual sensitivity. Common oral doses range from 30 to 120 mg. Lower doses are advised for new users. The effects can last between 4 to 8 hours, with an onset of 20 to 120 minutes.

Bijwerkingen:

Potential adverse effects include nausea, headache, increased heart rate, dehydration, and bruxism. Long-term or high-dose use may lead to neurotoxicity or serotonin syndrome. Psychological effects like anxiety and paranoia are possible.

Schadebeperking:

To minimize risks, it’s important to start with low doses and avoid mixing with other substances. Staying hydrated, taking breaks in cool environments, and having a sober companion can help mitigate physical and psychological risks. Pre and post-loading with antioxidants and staying informed about interactions are also advisable.

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