2-Methyl-PiHP (2-Me-PiHP) is a novel synthetic compound belonging to the pyrrolidine class of stimulants. Structurally related to α-Pyrrolidinohexiophenone (α-PiHP), 2-Me-PiHP exhibits similar pharmacological effects but features a methyl substitution at the 2-position of the phenyl ring. This minor structural modification significantly impacts the compound’s receptor affinity, potency, and duration of action. 2-Me-PiHP is primarily researched for its central nervous system (CNS) stimulating properties, often compared to cathinone derivatives such as α-PVP and α-PiHP. Due to its unique chemical profile, it is widely used in pharmacological studies exploring the mechanisms of stimulant-induced dopamine release and norepinephrine uptake inhibition.
Chemical Structure and Properties
- IUPAC名： 2-(Methylamino)-1-phenylpentan-1-one
- 分子式： C13H17NO
- 分子量： 203.28 g/mol
- SMILES Representation: CC(C)NC(=O)C1=CC=CC=C1
- Chemical Class: Pyrrolidine Stimulant
2-Me-PiHP is a highly lipophilic compound, enabling it to cross the blood-brain barrier efficiently. Its pharmacodynamics involve high-affinity binding to monoamine transporters, particularly the dopamine and norepinephrine transporters (DAT and NET), resulting in potent reuptake inhibition and increased synaptic neurotransmitter levels.
効果
The effects of 2-Me-PiHP, based on anecdotal reports and laboratory studies, include:
- 刺激： Enhanced physical and mental energy, often accompanied by heightened alertness and focus.
- 幸福感： A transient increase in mood and feelings of well-being.
- Increased Sociability: Users report heightened confidence and talkativeness.
- Cognitive Enhancement: Improved short-term memory, problem-solving abilities, and concentration.
The onset of effects is typically rapid, occurring within 15-30 minutes after administration, with peak effects observed around 1-2 hours. The total duration of action ranges from 4 to 6 hours, depending on dosage and individual metabolic factors.
投与ガイドライン
免責事項 All information is provided for research purposes only. Human consumption is not advised.
- Threshold: 5-10 mg
- 軽い： 10-20 mg
- よくあることだ： 20-30 mg
- 強い： 30-40 mg
Due to its potency, initial doses should be conservative to mitigate adverse reactions. Laboratory protocols should emphasize precise measurement using a milligram scale.
副作用
Potential adverse effects include:
- Psychological: Anxiety, paranoia, agitation, and restlessness.
- Physical: Increased heart rate, hypertension, sweating, and vasoconstriction.
- 神経学的： Headache, dizziness, and insomnia.
Prolonged or excessive use may exacerbate side effects, leading to tolerance, dependence, or neurotoxicity. Researchers should exercise caution during studies to limit dosage and exposure duration.
ハームリダクション
To ensure safe handling and minimize risks, the following harm reduction strategies are recommended:
Co-administration: Avoid mixing with other stimulants or depressants to reduce interaction risks.
Accurate Dosage: Utilize calibrated equipment for precise measurement.
Environment: Conduct experiments in a controlled and supervised setting.
Hydration: Maintain proper hydration levels to mitigate dehydration caused by excessive stimulation.
Breaks: Avoid repeated exposure and ensure adequate rest periods between experiments.
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What you will receive when you buy 2-Me-PiHP from RECHEMCO?
- 最高級のアルミ箔入り密封袋1袋 2-Me-PiHP
• white/yellowish crystals
- 98% 純度
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