Tadalafil API EU


Tadalafil is a medication used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It works by relaxing the blood vessels in the body, allowing for increased blood flow to the penis or lungs. Tadalafil is available in tablet form and is taken orally, usually 30 minutes before sexual activity. It has a longer duration of action compared to other ED medications, lasting up to 36 hours, earning it the nickname “the weekend pill”. Tadalafil is a prescription medication and should only be taken under the guidance of a healthcare professional.

All the products from EU Retail can be shipped to EU countries only.
All the designer drugs sold on this website are intended for research and forensic applications.

Tadalafil is a medication used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It is a potent and selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Tadalafil acts by increasing the blood flow to the penis, which leads to an erection. In PAH, tadalafil relaxes the blood vessels in the lungs, which allows blood to flow more easily.

Tadalafil is sold under the brand name Cialis and is available in tablet form. The tablets are available in strengths of 2.5mg, 5mg, 10mg, and 20mg. The recommended starting dose for ED is 10mg, taken at least 30 minutes before sexual activity. The dose may be increased to 20mg or decreased to 5mg, depending on the effectiveness and tolerability of the medication. The recommended dose for PAH is 40mg once daily.

Tadalafil has a long duration of action, with a half-life of approximately 17.5 hours. This means that it can remain in the body for up to 36 hours, allowing for spontaneous sexual activity. Tadalafil should not be taken more than once a day.

Tadalafil is metabolized primarily by the cytochrome P450 enzyme system, specifically CYP3A4, with a minor contribution from CYP2C9. The use of tadalafil is contraindicated in patients taking nitrates, as the combination may cause a severe and potentially life-threatening drop in blood pressure. Tadalafil should also be used with caution in patients with hepatic or renal impairment, as the drug is primarily eliminated through the liver and kidneys.

The most common side effects of tadalafil include headache, indigestion, back pain, muscle aches, flushing, and nasal congestion. These side effects are usually mild and transient, and tend to improve with continued use. However, patients should seek medical attention if they experience a sudden loss of vision or hearing, or if they experience an erection lasting longer than 4 hours, as these may be signs of a serious medical condition.

In conclusion, tadalafil is a highly effective and well-tolerated medication for the treatment of ED and PAH. It has a long duration of action, which allows for spontaneity in sexual activity. However, patients should be aware of the potential side effects and contraindications associated with the use of tadalafil, and should consult their healthcare provider before starting treatment.

Formal Name


Chemical Formula


Molecular Weight

389.411 g·mol−1


1g, 3g, 5g, 10g

1 review for Tadalafil API EU

  1. ke

    Great Substance! just sad that its jsut to buy in 1g Quantitys..250 or 500mg would be better i think.
    BUT: the half life is really really long..after 30hours an erection was still like instnt (lets say a litle too eas,,but goo ´d for each situationh 😉

    • Rechemco

      Thank you for sharing your experience with Tadalafil. It’s great to hear that you find it to be a helpful medication for erectile dysfunction.

      Regarding the quantity options, it seems that EU Retail currently offers Tadalafil in 1g quantities. While it’s understandable that you would prefer smaller quantities like 250 or 500mg, it’s worth noting that the availability of different dosage options may vary depending on the supplier or manufacturer.

      As for the long half-life of Tadalafil, which contributes to its extended duration of action, it’s important to remember that individual responses to medications can vary. It’s always recommended to follow the dosage instructions provided by your healthcare professional and to consult with them if you have any concerns or questions about the medication. Your healthcare professional can provide guidance based on your specific needs and circumstances.

      Thank you for sharing your feedback, and if you have any further questions or comments, feel free to let us know.

Add a review

Your email address will not be published. Required fields are marked *


  • Try your luck and win a discount coupon code
  • 1 free spin every 15 days
  • No cheating! Please use your real email address only.
  • REMEMBER: The validity of the coupon code is 7 days.
Try Your Luck!
Remind later
No thanks