{"id":51370,"date":"2025-07-14T06:43:22","date_gmt":"2025-07-14T06:43:22","guid":{"rendered":"https:\/\/rechemco.to\/?post_type=product&p=51370"},"modified":"2026-07-29T02:59:58","modified_gmt":"2026-07-29T02:59:58","slug":"sl-164-cn","status":"publish","type":"product","link":"https:\/\/rechemco.to\/ro\/sl-164-cn\/","title":{"rendered":"SL-164 CN Export \u2013 Angro"},"content":{"rendered":"

SL\u2011164 (Dicloqualone): Un Sedativ\/Hipnotic Chinazolinonic pentru Cercetare Avansat\u0103<\/strong><\/h3>\n\n\n\n
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\ud83e\uddec Prezentare general\u0103<\/h4>\n\n\n\n

SL\u2011164 (5\u2011clor\u20113\u2011(4\u2011clor\u20112\u2011metilfenil)\u20112\u2011metilchinazolin\u20114\u2011on\u0103), cunoscut \u0219i ca Dicloqualone<\/strong>, este un produs sintetic chinazolinon\u0103<\/strong> derivat dezvoltat la sf\u00e2r\u0219itul anilor 1960 de Sumitomo. Proiectat ca un analog structural al methaqualone (Quaalude), SL\u2011164 prezint\u0103 sedativ<\/strong>, hipnotic<\/strong>, \u0219i relaxant muscular<\/strong> propriet\u0103\u021bi. De\u0219i nu a fost niciodat\u0103 aprobat pentru uz clinic din cauza riscului mai mare de convulsii, serve\u0219te ca un instrument molecular valoros \u00een neuro\u0219tiin\u021b\u0103 \u0219i toxicologie criminalistic\u0103.<\/p>\n\n\n\n

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\u2699\ufe0f Propriet\u0103\u021bi chimice \u0219i fizice<\/h3>\n\n\n\n
    \n
  • Denumire IUPAC:<\/strong> 5\u2011Chloro\u20113\u2011(4\u2011chloro\u20112\u2011methylphenyl)\u20112\u2011methylquinazolin\u20114\u2011one<\/li>\n\n\n\n
  • Formul\u0103 molecular\u0103:<\/strong> C\u2081\u2086H\u2081\u2082Cl\u2082N\u2082O<\/li>\n\n\n\n
  • Greutate molecular\u0103:<\/strong> ~319,19\u202fg\/mol<\/li>\n\n\n\n
  • Form\u0103 fizic\u0103:<\/strong> Pulbere cristalin\u0103, solubil\u0103 \u00een DMF, DMSO, etanol<\/li>\n<\/ul>\n\n\n\n
    \n\n\n\n

    \ud83e\udde0 Mecanism de ac\u021biune<\/h3>\n\n\n\n

    SL\u2011164 ac\u021bioneaz\u0103 ca un modulator alosteric pozitiv<\/strong> la receptorii GABA\u2090, intensific\u00e2nd fluxul de clor inhibitor\u2014similar cu metacvalona \u0219i barbituricele\u2014produc\u00e2nd efecte sedativ-hipnotice. De asemenea, are activitate anticonvulsivant\u0103<\/strong>, dar cu un risc notabil de inducere a convulsiilor la doze mari.<\/p>\n\n\n\n

    \n\n\n\n

    \ud83d\udccc Profil farmacologic<\/h3>\n\n\n\n

    Efecte sedative \u0219i hipnotice<\/h4>\n\n\n\n

    \u00cen studiile preclinice, SL\u2011164 a indus sedare \u0219i hipnoz\u0103 similare cu metacvalona, de\u0219i nu a fost dezvoltat din cauza riscului de convulsii.<\/p>\n\n\n\n

    Activitate anticonvulsivant\u0103<\/h4>\n\n\n\n

    Modelele timpurii pe roz\u0103toare au demonstrat suprimarea convulsiilor, dar evenimentele adverse \u0219i convulsiile au \u00eempiedicat dezvoltarea ulterioar\u0103. .<\/p>\n\n\n\n

    Toxicologie \u0219i incidente clinice<\/h4>\n\n\n\n

    Dou\u0103 intoxica\u021bii documentate (v\u00e2rste ~21\u201322) au implicat doze mari (~300\u202fmg oral), rezult\u00e2nd \u00een delir agitat<\/strong>, mioclonus<\/strong>, tahicardie<\/strong>, \u0219i sedare prelungit\u0103<\/strong>, gestionat prin \u00eengrijire de sus\u021binere \u0219i benzodiazepine.<\/p>\n\n\n\n

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    \ud83d\udc8a Dozaj \u0219i administrare (Context de cercetare)<\/h3>\n\n\n\n

    SL\u2011164 is used solely in standard analitic<\/strong> sau studiu pe animale<\/strong> set\u0103ri. Nu exist\u0103 dozare clinic\u0103 la om. Dac\u0103 se administreaz\u0103 in vivo, \u00eencepe\u021bi cu microgram\u2013miligram<\/strong> doze la roz\u0103toare, prin injectare sau gavaj oral. Respecta\u021bi \u00eentotdeauna ghidurile etice \u0219i legale<\/p>\n\n\n\n

    \n\n\n\n

    \u26a0\ufe0f Efecte secundare \u0219i siguran\u021b\u0103<\/h3>\n\n\n\n
      \n
    • SNC:<\/strong> Sedare, ataxie, afectare cognitiv\u0103<\/li>\n\n\n\n
    • Excita\u021bie paradoxal\u0103:<\/strong> La doze mari\u2014delir sau convulsii<\/li>\n\n\n\n
    • Autonom:<\/strong> Tahicardie, hipertensiune \u00een supradoz\u0103<\/li>\n\n\n\n
    • Respirator\/CV:<\/strong> Risc sc\u0103zut, dar deprimat \u00een cazurile de intoxica\u021bii severe.<\/li>\n<\/ul>\n\n\n\n

      Utiliza\u021bi \u00een experimente controlate cu monitorizarea convulsiilor \u0219i protocoale de urgen\u021b\u0103.<\/p>\n\n\n\n

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      \ud83d\udd12 Reducerea riscurilor \u0219i siguran\u021ba \u00een laborator<\/h3>\n\n\n\n
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      • Preg\u0103ti\u021bi solu\u021bii stoc precise<\/strong>, a se p\u0103stra la \u221220\u202f\u00b0C<\/li>\n\n\n\n
      • Utilizare c\u00e2ntare de precizie mg<\/strong><\/li>\n\n\n\n
      • Evita\u021bi administrarea concomitent\u0103 cu Depresive ale SNC<\/strong><\/li>\n\n\n\n
      • Asigura\u021bi m\u0103suri de \u00eengrijire suportiv\u0103<\/strong> disponibile pentru convulsii<\/li>\n<\/ul>\n\n\n\n
        \n\n\n\n

        \ud83d\udd16 Statut legal \u0219i de cercetare<\/h3>\n\n\n\n
          \n
        • Nu este comercializat clinic<\/strong>; doar pentru uz de cercetare<\/strong><\/li>\n\n\n\n
        • Aprovizionarea online mai ieftin\u0103 a stimulat abuzul de droguri de designer<\/strong><\/li>\n\n\n\n
        • Statutul de reglementare variaz\u0103<\/strong>; legal \u00een conformitate cu legile privind medicamentele sau drogurile analoge<\/li>\n<\/ul>\n\n\n\n
          \n\n\n\n

          \ud83e\uddea Rezumat<\/h3>\n\n\n\n

          SL\u2011164 este un compus intrigant din punct de vedere chimic \u0219i semnificativ biologic sedative-hypnotic<\/strong> agent cu at\u00e2t utilitate, c\u00e2t \u0219i risc. Fiind un analog al metacualonei, acesta poart\u0103 Poten\u021b\u0103 GABAergic\u0103<\/strong>, valoare experimental\u0103 \u0219i importan\u021b\u0103 criminalistic\u0103. Utiliza\u021bi \u00een numai protocoale de laborator aprobate<\/strong>.<\/p>\n\n\n\n

          \n\n\n\n

          De ce s\u0103 cump\u0103ra\u021bi\u00a0SL\u2011164<\/strong> CN Export<\/strong><\/strong>\u00a0de la RECHEMCO?<\/h2>\n\n\n\n

          \u2605 Avem o lung\u0103 istorie comercial\u0103 pe pia\u021b\u0103, astfel \u00eenc\u00e2t s\u0103 beneficia\u021bi de experien\u021ba noastr\u0103.
          \u2605\u00a0SL\u2011164<\/strong>\u00a0a fost testat\u0103 \u0219i verificat\u0103.
          \u2605 Accept\u0103m diferite metode de plat\u0103, cum ar fi Bitcoin, Monero \u0219i s\u00e2rm\u0103 bancar\u0103.<\/p>\n\n\n\n

          Ce ve\u021bi primi atunci c\u00e2nd cump\u0103ra\u021bi\u00a0SL\u2011164 CN Export<\/strong>\u00a0de la RECHEMCO?<\/h3>\n\n\n\n

          - O pung\u0103 sigilat\u0103 din folie de aluminiu care con\u021bine cea mai bun\u0103 calitate\u00a0SL\u2011164 CN Export<\/strong>
          - Pulbere alb\u0103
          \u2022 Puritate 99%<\/p>\n\n\n\n

          <\/p>","protected":false},"excerpt":{"rendered":"

          SL\u2011164 (Dicloqualon\u0103) \u2013 Compus de cercetare chinazolinonic sedativ-hipnotic<\/h2>\n

          SL\u2011164<\/strong> este un puternic **derivat de chinazolinon\u0103** \u0219i analog de metacvalon\u0103 dezvoltat \u00een anii 1960. Ac\u021bioneaz\u0103 ca **modulator al receptorului GABA_A**, produc\u00e2nd efecte sedative, hipnotice \u0219i anticonvulsivante \u00een modelele animale.<\/p>\n

            \n
          • Structural analogue of methaqualone (Quaalude)<\/li>\n
          • Modulator alosteric pozitiv al receptorilor GABA_A<\/li>\n
          • Util ca standard de referin\u021b\u0103 analitic\u0103 pentru analizele LC-MS criminalistice<\/li>\n
          • Poten\u021bial de convulsii \u0219i delir la doze mari<\/li>\n<\/ul>\n

            Toate produsele din CN Export - Wholesale sunt livrate din China.<\/strong><\/p>\n

            \u00cen caz de pierdere sau de confiscare de c\u0103tre autorit\u0103\u021bile vamale locale: NU se fac ramburs\u0103ri sau reclama\u021bii.<\/strong><\/p>\n

            Toate drogurile artizanale v\u00e2ndute pe acest site sunt destinate cercet\u0103rii \u0219i aplica\u021biilor criminalistice.<\/strong><\/p>","protected":false},"featured_media":51377,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[15],"product_tag":[1757,1741,1743,1750,1756,1748,1751,1746,1759,1752,1755,1758,1745,1753,1747,1749,1754,1744,1742,1740],"class_list":["post-51370","product","type-product","status-publish","has-post-thumbnail","product_cat-out-of-stock","product_tag-anticonvulsant-compound","product_tag-cns-depressant-analogue","product_tag-designer-drug-sl164","product_tag-dicloqualone","product_tag-forensic-reference-standard","product_tag-forensic-toxicology-tool","product_tag-gaba_a-modulator","product_tag-gabaergic-research-molecule","product_tag-lc-qtof-ms-analytical-standard","product_tag-methaqualone-analogue","product_tag-psychotropic-quinazolinone","product_tag-quinazolinone-sedative","product_tag-research-only-substance","product_tag-sedative-hypnotic-research-chemical","product_tag-seizure-risk-sedative","product_tag-sl164","product_tag-sl164-animal-studies","product_tag-sl164-toxicity","product_tag-structural-analogue-of-quaalude","product_tag-synthetic-sedative-hypnotic","first","outofstock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/product\/51370","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/comments?post=51370"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/media\/51377"}],"wp:attachment":[{"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/media?parent=51370"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/product_brand?post=51370"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/product_cat?post=51370"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/product_tag?post=51370"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}