{"id":28781,"date":"2023-10-02T06:33:05","date_gmt":"2023-10-02T06:33:05","guid":{"rendered":"https:\/\/rechemco.to\/?post_type=product&#038;p=28781"},"modified":"2025-11-24T02:27:30","modified_gmt":"2025-11-24T02:27:30","slug":"zanaflex-2mg-tizanidine","status":"publish","type":"product","link":"https:\/\/rechemco.to\/ro\/zanaflex-2mg-tizanidine\/","title":{"rendered":"Zanaflex 2mg Tizanidine INDIA"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Zanaflex (Tizanidine) este un agonist \u03b12-adrenergic cu ac\u021biune central\u0103 care este utilizat ca relaxant muscular. Principalul s\u0103u ingredient activ, tizanidina, func\u021bioneaz\u0103 \u00een principal \u00een sistemul nervos central pentru a produce efectele sale relaxante musculare. Denumirea chimic\u0103 a Tizanidinei este 5-cloro-4-(2-imidazolin-2-ilamino)-2,1,3-benzotiadiazol.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Farmacodinamic\u0103:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Tizanidina \u00ee\u0219i exercit\u0103 efectul terapeutic prin inhibarea neuronilor motori presinaptici, ceea ce duce la o reducere a spasticit\u0103\u021bii. Prin cre\u0219terea inhibi\u021biei presinaptice a neuronilor motori, Tizanidina reduce eliberarea de aminoacizi excitan\u021bi \u0219i scade rata de ardere a neuronilor motori, suprim\u00e2nd astfel hiperactivitatea reflex\u0103.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Utiliz\u0103ri:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Zanaflex 2mg este indicat pentru gestionarea spasticit\u0103\u021bii, care poate ap\u0103rea \u00een urma unei variet\u0103\u021bi de afec\u021biuni, inclusiv scleroza multipl\u0103, leziuni ale m\u0103duvei spin\u0103rii sau alte afec\u021biuni neurologice. Spasticitatea este o afec\u021biune \u00een care mu\u0219chii se contract\u0103 \u00een mod continuu, provoc\u00e2nd rigiditate sau \u00eencordare a mu\u0219chilor \u0219i poate interfera cu mi\u0219carea, vorbirea \u0219i mersul.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Prin reducerea spasticit\u0103\u021bii, Zanaflex ajut\u0103 la \u00eembun\u0103t\u0103\u021birea tonusului muscular, amelioreaz\u0103 durerea \u0219i \u00eencordarea muscular\u0103 \u0219i ajut\u0103 la restabilirea mi\u0219c\u0103rilor normale.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Dozaj:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Doza ini\u021bial\u0103 recomandat\u0103 de Zanaflex este de 2 mg. \u00cen func\u021bie de nevoile individuale ale pacientului \u0219i de r\u0103spunsul acestuia, doza poate fi ajustat\u0103 la intervale de 24 de ore. Doza poate fi crescut\u0103 cu 2-4mg p\u00e2n\u0103 c\u00e2nd se ob\u021bine un r\u0103spuns optim. Cu toate acestea, doza zilnic\u0103 total\u0103 nu trebuie s\u0103 dep\u0103\u0219easc\u0103 36mg. Este important de re\u021binut c\u0103 tratamentul trebuie s\u0103 fie individualizat \u00een func\u021bie de nevoile \u0219i r\u0103spunsul pacientului.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Considera\u021bii privind dozajul:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Timing cu alimente<\/strong>: Zanaflex este cunoscut pentru a cre\u0219te biodisponibilitatea sa atunci c\u00e2nd este administrat cu alimente. Pacien\u021bii trebuie s\u0103 fie consecven\u021bi \u00een a lua Zanaflex fie \u00eentotdeauna cu sau \u00eentotdeauna f\u0103r\u0103 alimente.<\/li>\n\n\n\n<li><strong>Titrarea dozelor<\/strong>: Pentru a minimiza riscul de apari\u021bie a reac\u021biilor adverse, se recomand\u0103 titrarea lent\u0103 a dozei la ini\u021bierea tratamentului.<\/li>\n\n\n\n<li><strong>Retragere<\/strong>: \u00centreruperea brusc\u0103 poate duce la hipertensiune arterial\u0103 de rebound \u0219i tahicardie; se recomand\u0103 reducerea treptat\u0103 a dozei.<\/li>\n\n\n\n<li><strong>Insuficien\u021b\u0103 renal\u0103<\/strong>: Pacien\u021bii cu insuficien\u021b\u0103 renal\u0103 pot necesita doze reduse. Este esen\u021bial s\u0103 se monitorizeze \u00eendeaproape ace\u0219ti pacien\u021bi.<\/li>\n\n\n\n<li><strong>Pacien\u021bi v\u00e2rstnici<\/strong>: Popula\u021bia v\u00e2rstnic\u0103 ar putea avea o func\u021bie renal\u0103 redus\u0103; prin urmare, ar putea necesita doze reduse.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Efecte secundare:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Reac\u021biile adverse frecvente includ somnolen\u021b\u0103, gur\u0103 uscat\u0103, astenie, ame\u021beli, infec\u021bii ale tractului urinar \u0219i probleme gastrointestinale. Este esen\u021bial s\u0103 se monitorizeze hipotensiunea, anomaliile func\u021biei hepatice \u0219i semnele de depresie a sistemului nervos central.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Contraindica\u021bii \u0219i avertismente:<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Zanaflex nu trebuie utilizat concomitent cu inhibitori ai CYP1A2, cum ar fi fluvoxamina sau ciprofloxacina.<\/li>\n\n\n\n<li>Utilizarea concomitent\u0103 a Zanaflex cu alte deprimante ale SNC poate poten\u021ba efectele asupra SNC.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Depozitare:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A se p\u0103stra la o temperatur\u0103 cuprins\u0103 \u00eentre 15\u00b0C \u0219i 30\u00b0C. A nu se p\u0103stra la \u00eendem\u00e2na copiilor.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Denumirea produsului:<\/strong> Zanaflex 2mg (Tizanidine)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Descriere:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Zanaflex 2mg este un agonist alfa-2 adrenergic cu ac\u021biune central\u0103, ingredientul s\u0103u principal fiind Tizanidina. Acest medicament este utilizat cu prec\u0103dere ca antispastic pentru a oferi u\u0219urare \u00een cazul spasmelor, crampe, \u00een\u0103sprirea mu\u0219chilor \u0219i alte afec\u021biuni asociate.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Structura chimic\u0103:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Clorhidratul de tizanidin\u0103 (HCl) este o pulbere cristalin\u0103 fin\u0103, alb\u0103 p\u00e2n\u0103 la albicioas\u0103, inodor\u0103 sau cu un miros caracteristic slab. Este u\u0219or solubil\u0103 \u00een ap\u0103 \u0219i metanol \u0219i solubil\u0103 \u00een etanol.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Utiliz\u0103ri:<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Spasticitate muscular\u0103:<\/strong> Zanaflex este indicat \u00een principal pentru tratamentul spasticit\u0103\u021bii musculare. Spasticitatea muscular\u0103 ar putea fi cauzat\u0103 de scleroz\u0103 multipl\u0103, leziuni ale m\u0103duvei spin\u0103rii sau alte afec\u021biuni neurologice.<\/li>\n\n\n\n<li><strong>Utiliz\u0103ri \u00een afara etichetei:<\/strong> Au existat cazuri \u00een care Tizanidina este utilizat\u0103 pentru migrene, tulbur\u0103ri de cefalee \u0219i ca ajutor pentru somn. Consulta\u021bi \u00eentotdeauna un profesionist medical \u00eenainte de a lua acest medicament \u00een scopuri off-label.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Dozare \u0219i administrare:<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Doza de pornire:<\/strong> Pentru majoritatea pacien\u021bilor, doza ini\u021bial\u0103 recomandat\u0103 este de 2 mg. \u00cen func\u021bie de r\u0103spunsul pacientului, doza poate fi crescut\u0103 cu cre\u0219teri de 2 mg p\u00e2n\u0103 la 4 mg p\u00e2n\u0103 la ob\u021binerea unui r\u0103spuns optim.<\/li>\n\n\n\n<li><strong>Doza de \u00eentre\u021binere:<\/strong> Dozajul poate fi crescut treptat cu 2 mg p\u00e2n\u0103 la 4 mg la fiecare doz\u0103, cu 1 p\u00e2n\u0103 la 4 zile \u00eentre cre\u0219teri, p\u00e2n\u0103 c\u00e2nd se ob\u021bine o reducere satisf\u0103c\u0103toare a tonusului muscular. Doza zilnic\u0103 total\u0103 nu trebuie s\u0103 dep\u0103\u0219easc\u0103 36 mg.<\/li>\n\n\n\n<li><strong>Dozajul la popula\u021bii specifice:<\/strong> Pentru pacien\u021bii v\u00e2rstnici sau cei cu insuficien\u021b\u0103 renal\u0103, doza trebuie ajustat\u0103 corespunz\u0103tor, lu\u00e2nd \u00een considerare clearance-ul creatininei individului.<\/li>\n\n\n\n<li><strong>Administra\u021bie:<\/strong> Zanaflex 2mg trebuie administrat pe cale oral\u0103 cu un pahar plin de ap\u0103. Poate fi administrat cu sau f\u0103r\u0103 alimente, dar administrarea constant\u0103, fie cu alimente, fie f\u0103r\u0103, va asigura o absorb\u021bie mai uniform\u0103.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Contraindica\u021bii:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Zanaflex 2mg nu trebuie utilizat:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>De c\u0103tre pacien\u021bii cu hipersensibilitate la Tizanidin\u0103 sau la oricare dintre celelalte componente ale tabletei.<\/li>\n\n\n\n<li>Concomitent cu inhibitori puternici ai CYP1A2.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Efecte secundare:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Reac\u021biile adverse frecvente includ usc\u0103ciunea gurii, somnolen\u021b\u0103, astenie (sl\u0103biciune sau oboseal\u0103), ame\u021beli, ITU (infec\u021bie a tractului urinar), constipa\u021bie, anomalii ale testelor func\u021biei hepatice, v\u0103rs\u0103turi \u0219i tulbur\u0103ri de vorbire. Aceasta nu este o list\u0103 complet\u0103, iar pacien\u021bii trebuie s\u0103 consulte un profesionist din domeniul s\u0103n\u0103t\u0103\u021bii pentru informa\u021bii detaliate.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Depozitare:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A se p\u0103stra la 25\u00b0C (77\u00b0F); sunt permise excursii la 15-30\u00b0C (59-86\u00b0F) \u00eentr-un loc uscat \u0219i a se \u021bine departe de accesul copiilor.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Not\u0103:<\/strong> Consulta\u021bi \u00eentotdeauna un medic \u00eenainte de a \u00eencepe sau de a \u00eentrerupe orice medicament. Aceast\u0103 descriere nu con\u021bine toate efectele secundare sau interac\u021biunile posibile.<\/p>","protected":false},"excerpt":{"rendered":"<div class=\"product-description\">\n<h2>Zanaflex 2mg Tizanidine<\/h2>\n<p>C\u0103uta\u021bi o u\u0219urare a spasticit\u0103\u021bii musculare? Descoperi\u021bi <span class=\"highlight\">Zanaflex<\/span>, relaxant muscular cu ac\u021biune central\u0103 care amelioreaz\u0103 tensiunea muscular\u0103 \u0219i durerea. Perfect pentru cei cu afec\u021biuni precum scleroza multipl\u0103 sau leziuni ale m\u0103duvei spin\u0103rii.<\/p>\n<p><strong>Dozaj:<\/strong> \u00cencepe\u021bi cu 2mg \u0219i ajusta\u021bi \u00een func\u021bie de nevoile dumneavoastr\u0103. Nu uita\u021bi, consecven\u021ba este cheia; lua\u021bi-o cu sau f\u0103r\u0103 m\u00e2ncare, dar r\u0103m\u00e2ne\u021bi consecvent. Doza zilnic\u0103 maxim\u0103: 36mg.<\/p>\n<p><strong>Not\u0103:<\/strong> Efectele secundare pot include somnolen\u021b\u0103 sau ame\u021beli. Consulta\u021bi \u00eentotdeauna medicul dumneavoastr\u0103 \u00eenainte de a \u00eencepe un nou medicament.<\/p>\n<p>Toate medicamentele INDIA MEDS sunt expediate prin curier \u0219i num\u0103r de urm\u0103rire \u00een 48 de ore de la efectuarea pl\u0103\u021bii.<br \/>Timp mediu de livrare: 2-3 s\u0103pt\u0103m\u00e2ni.<\/p>\n<\/div>","protected":false},"featured_media":28786,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[101,105],"product_tag":[813,816,811,810,815,817,806,249,814,809,819,475,808,812,818,617,252,805,647,807],"class_list":["post-28781","product","type-product","status-publish","has-post-thumbnail","product_cat-india-meds","product_cat-painkillers-in","product_tag-central-nervous-system","product_tag-cns-depressants","product_tag-contraindications","product_tag-dosage-titration","product_tag-elderly-patients","product_tag-medication","product_tag-multiple-sclerosis","product_tag-muscle-relaxant","product_tag-muscle-tightness","product_tag-neurological-disorders","product_tag-optimal-response","product_tag-pain-relief","product_tag-pharmacodynamics","product_tag-recommended-dosage","product_tag-renal-impairment","product_tag-side-effects","product_tag-spasticity","product_tag-tizanidine","product_tag-treatment","product_tag-zanaflex","first","outofstock","shipping-taxable","purchasable","product-type-variable","has-default-attributes"],"_links":{"self":[{"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/product\/28781","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/comments?post=28781"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/media\/28786"}],"wp:attachment":[{"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/media?parent=28781"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/product_brand?post=28781"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/product_cat?post=28781"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/rechemco.to\/ro\/wp-json\/wp\/v2\/product_tag?post=28781"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}