{"id":58446,"date":"2025-10-20T07:23:17","date_gmt":"2025-10-20T07:23:17","guid":{"rendered":"https:\/\/rechemco.to\/?post_type=product&#038;p=58446"},"modified":"2026-07-29T02:59:39","modified_gmt":"2026-07-29T02:59:39","slug":"exportation-en-gros-de-pynazolam-cn","status":"publish","type":"product","link":"https:\/\/rechemco.to\/fr\/pynazolam-cn-export-wholesale\/","title":{"rendered":"Pynazolam CN Export \u2013 Vente en gros"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Pynazolam \u2013 Triazolobenzodiazepine Derivative (Research Use Only)<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Overview<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Pynazolam is a synthetic benzodiazepine derivative of the triazolo-benzodiazepine (TBZD) class. It was first described in the 1970s but was never developed for clinical use.<br>It has emerged in recent years as a \u201cdesigner benzodiazepine\u201d \/ novel psychoactive substance (NPS) and is of interest in forensic toxicology, GABA&lt;sub>A&lt;\/sub> receptor research, and structure-activity relationship (SAR) studies.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Chemical Identity &amp; Structure<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>IUPAC Name:<\/strong> 1-methyl-8-nitro-6-(pyridin-2-yl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine<\/li>\n\n\n\n<li><strong>Molecular Formula:<\/strong> C\u2081\u2086H\u2081\u2082N\u2086O\u2082<\/li>\n\n\n\n<li><strong>CAS Number:<\/strong> 2034366-97-5<\/li>\n\n\n\n<li><strong>Class:<\/strong> Triazolobenzodiazepine (TBZD)<\/li>\n\n\n\n<li><strong>Appearance:<\/strong> Typically supplied as research grade powder or salt (analytical standard)<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Mechanism of Action (Inference)<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">As a benzodiazepine analog, Pynazolam is presumed to act as a <strong>positive allosteric modulator<\/strong> of the GABA&lt;sub>A&lt;\/sub> receptor. By binding to the benzodiazepine site, it enhances GABA-mediated chloride flux, causing neuronal hyperpolarization and CNS depression.<br>Designer benzodiazepines of the TBZD class are known to exhibit strong sedative, anxiolytic, muscle-relaxant, hypnotic, and amnestic effects\u2014though the precise pharmacology of Pynazolam remains largely uncharacterised.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Pharmacological &amp; Toxicological Considerations<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>There is limited published data on human pharmacokinetics or clinical use of Pynazolam. In silico and experimental modelling suggest <strong>high potency<\/strong>, and typical \u201cdesigner benzodiazepine\u201d risk profiles apply.<\/li>\n\n\n\n<li>Designer benzodiazepines have been implicated in hospitalisations, impaired driving, and fatalities\u2014especially when used with opioids, alcohol or other depressants.<\/li>\n\n\n\n<li>Given the unknown therapeutic index and high potency, laboratory handling must assume <strong>narrow margin between effect and toxicity<\/strong>.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Analytical &amp; Forensic Applications<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Pynazolam can be used as a reference compound in:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>LC-MS\/MS and GC-MS method validation for designer benzodiazepine detection<\/li>\n\n\n\n<li>Forensic toxicology screening of NPS-related intoxications<\/li>\n\n\n\n<li>SAR studies exploring how the 8-nitro and pyridinyl substitutions affect receptor binding and metabolism<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Safety, Handling &amp; Laboratory Precautions<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Use only in licensed, well-equipped laboratories<\/li>\n\n\n\n<li>Employ PPE: gloves, eye protection, respirator (if aerosol risk)<\/li>\n\n\n\n<li>Use analytical precision balances and avoid cross-contamination<\/li>\n\n\n\n<li>Dispose in compliance with institutional chemical hazard protocols<\/li>\n\n\n\n<li>Label clearly: <em>For Analytical\/Forensic Use Only \u2013 Not for Human Consumption<\/em><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Legal &amp; Regulatory Status<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Pynazolam is an unapproved psychoactive substance. Many jurisdictions regulate designer benzodiazepines under analogue laws or specific controls.<\/li>\n\n\n\n<li>Researchers must verify <strong>local controlled-substance classification<\/strong> and institutional compliance prior to acquisition or use.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Summary<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Pynazolam is a potent triazolobenzodiazepine analogue with forensic and pharmacological significance. Its structural modifications (8-nitro group, pyridinyl substitution) make it relevant for GABA&lt;sub&gt;A&lt;\/sub&gt; receptor studies and designer benzodiazepine monitoring. Given its unknown human profile and high potency, it demands rigorous analytical handling and is strictly for research use.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Why Buy\u00a0<strong>Pynazolam<\/strong>\u00a0from RECHEMCO?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u2605\u00a0We have a long trading history in the market so you benefit from our experience. <br>\u2605\u00a0<strong><strong>Pynazolam<\/strong><\/strong>\u00a0was tested and verified.<br>\u2605\u00a0We accept various payment methods such as Bitcoin, the main cryptocurrencies, Credit Card via Plisio and bank wire.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What you will receive when you buy\u00a0<strong><strong><strong><strong>Pynazolam<\/strong><\/strong><\/strong><\/strong>\u00a0from RECHEMCO?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u2022\u00a0One sealed aluminum foil bag containing highest grade\u00a0<strong><strong><strong>Pynazolam<\/strong><\/strong><\/strong><br>\u2022\u00a0white\/yellowish powder<br>\u2022\u00a099% Purity<\/p>\n","protected":false},"excerpt":{"rendered":"<h2>Pynazolam \u2013 Triazolobenzodiazepine Research Standard<\/h2>\n<p><strong>Pynazolam<\/strong> est un <strong>triazolobenzodiazepine analogue<\/strong> related to classical benzodiazepines, acting as a GABA<sub>A<\/sub> receptor modulator.<br \/>\nIt is studied in <strong>toxicologie m\u00e9dico-l\u00e9gale<\/strong> et <strong>la recherche pharmacologique<\/strong> for its unique pyridinyl and nitro substitutions that influence receptor binding and potency.<\/p>\n<ul>\n<li>For LC\u2013MS\/MS and GC\u2013MS analytical validation<\/li>\n<li>Used in SAR and designer benzodiazepine profiling<\/li>\n<li>Handle under laboratory safety protocols<\/li>\n<\/ul>\n<p><em>For research and analytical reference only. Not for human consumption.<\/em><\/p>\n<p><em>Non destin\u00e9 \u00e0 un usage humain ou v\u00e9t\u00e9rinaire. Manipuler avec une extr\u00eame prudence dans un environnement de laboratoire contr\u00f4l\u00e9.<\/em><\/p>\n<p><strong>Pynazolam<\/strong> est pr\u00eat \u00e0 \u00eatre exp\u00e9di\u00e9 dans les 48h-72h apr\u00e8s le paiement.<\/p>\n<p>D\u00e9lai moyen de livraison : 1 mois.<\/p>\n<p><strong>Toutes les drogues de synth\u00e8se vendues sur ce site sont destin\u00e9es \u00e0 la recherche et aux applications m\u00e9dico-l\u00e9gales.<\/strong><\/p>\n<p><b>ATTENTION !<br \/><\/b>En cas de perte, d'adresse erron\u00e9e ou de tout autre probl\u00e8me, aucune r\u00e9exp\u00e9dition ni remboursement n'est autoris\u00e9 pour ce produit.<\/p>\n<p>&nbsp;<\/p>","protected":false},"featured_media":58422,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[15],"product_tag":[1853,1861,1855,1863,1856,1849,1846,1851,1858,1848,1850,1852,1857,1862,1845,1847,1860,1312,1859,1854],"class_list":["post-58446","product","type-product","status-publish","has-post-thumbnail","product_cat-out-of-stock","product_tag-analytical-reference-benzodiazepine","product_tag-benzimidazodiazepine","product_tag-benzodiazepine-analog","product_tag-benzodiazepine-analog-toxicology","product_tag-benzodiazepine-metabolism-studies","product_tag-benzodiazepine-pharmacology","product_tag-benzodiazepine-potency-study","product_tag-benzodiazepine-receptor-binding-study","product_tag-benzodiazepine-sar-research","product_tag-cns-depressant-reference","product_tag-diazepine-research-compound","product_tag-fluoprazolam","product_tag-forensic-benzodiazepine-standard","product_tag-gaba-a-receptor-modulator","product_tag-lab-use-only-benzodiazepine","product_tag-nitro-diazepine-ligand","product_tag-nitrobenzodiazepine","product_tag-novel-benzodiazepine","product_tag-piperazinylmethylene-benzodiazepine","product_tag-sedative-hypnotic-research","first","outofstock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/rechemco.to\/fr\/wp-json\/wp\/v2\/product\/58446","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rechemco.to\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/rechemco.to\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/rechemco.to\/fr\/wp-json\/wp\/v2\/comments?post=58446"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/rechemco.to\/fr\/wp-json\/wp\/v2\/media\/58422"}],"wp:attachment":[{"href":"https:\/\/rechemco.to\/fr\/wp-json\/wp\/v2\/media?parent=58446"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/rechemco.to\/fr\/wp-json\/wp\/v2\/product_brand?post=58446"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/rechemco.to\/fr\/wp-json\/wp\/v2\/product_cat?post=58446"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/rechemco.to\/fr\/wp-json\/wp\/v2\/product_tag?post=58446"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}